Our brains are continually in the process of growing, shrinking, and killing neurons. By the way, that three-pound mass of tissue and fluid in our skulls consists of some 100 billion of them. And they’re party to an estimated 40 quadrillion, that’s 15 zeros, potential synaptic connections. Wow!
The activity of the brain is a miraculous never-ending balancing act, and problems arise when the scale is tipped toward neural shrinkage or death. The result can be anxiety and mood issues, as well as other mind variances. For example, brain imaging has revealed key-area brain shrinkage of as much as 10%-15% in chronic depression sufferers.
The term used for neural shrinkage is atrophy, and the chemicals that cause atrophy are known as atrophics. So, for example, the chemicals generated and released as a result of stress, most notably cortisol, are atrophics. Chemicals that foster neural growth, such as the antidepressants so often used in the treatment of panic and depression, are known as trophics. In short, then, neural growth, shrinkage, and death are to a large degree caused by the action of atrophic and trophic agents.
Neurogenesis is the process by which neurons are created. And though it makes perfect sense that it’s most active during prenatal development, the process continues on a much smaller scale into adulthood, even our senior years.
It’s so important to understand the dynamics of neurogenesis actually have the ability to reverse, if you will, all sorts of mental and emotional distress. That’s correct, in the face of targeted and appropriate intervention our brains can grow fresh neurons that serve to facilitate, enhance, and support newly learned coping skills, allowing us to feel one heck of a lot better. But, think about it, if one’s mental or emotional state improves, didn’t something brain-biological have to have happened?
For instance, the dentate gyrus of the hippocampus is an area of the brain in which neurogenesis is particularly active. See, the hippocampus, a component of the limbic system, is all about memory, learning, and emotion; all of which play major roles in anxiety and mood. Indeed, it’s been suggested that decreased hippocampal neurogenesis may be linked to increases in depression, which can be reversed by, say, the use of antidepressants – trophics.
So how ‘bout a short list of neurogenesis friendly factors. First of all, we have to include any medication with anti-panic, antidepressant, mood-stabilizing, and atypical antipsychotic characteristics. Incidentally, I’m not recommending these meds, just stating biochemical fact. And neurogenesis is also encouraged by mentally, emotionally, and physically healthy environments and lifestyle habits. Included are exercise, learning and memory work, spirituality, and psychotherapy. By the way, research has shown that one of the reasons all of these factors support neural growth and survival is because they increase levels of brain-derived neurotrophic factor (BDNF). Note the word, “neuroTROPHIC.”
On the other side of the fence, neurogenesis has its enemies. First in line is any sort of over-the-top or chronic stress. And that’s because it results in the secretion of the glucocorticoids, a family of steroids produced in the adrenal glands necessary for the regulation of energy metabolism and immune and inflammatory responses. The “stress hormone,” cortisol, is responsible for the vast majority of glucocorticoid activity. And though we need cortisol to increase our blood sugar and blood pressure levels in response to stress, too much of it for a long period of time can be a major problem.
One other neurogenesis adversary worth mentioning is excesses of glutamate, the brain’s most abundant excitatory, action-generating, neurotransmitter. It’s especially a factor during trauma and hypoglycemic events.
Absolutely, neurogenesis is a marvelous biochemical phenomenon that can really work to our advantage. And choice directs the outcome.
Original article here
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