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Neglecting your eyes can influence dementia Elderly people with untreated poor vision are significantly more likely to suffer from Alzheimer’s disease and other forms of dementia than their clear-sighted counterparts, according to a study published...

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Blueberry juice improves memory A new study shows that drinking a daily dose of wild blueberry juice improved the memory of older adults with age-related memory problems. It's the first study to show this potential benefit of blueberries...

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Pump up your hippo for a better functioning brain The role of some brain structures are better understood than others. For example, the hippocampus, a small S-shaped structure that lies just inside your temples, plays a specific role in memory for facts,...

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Australian research shows key to healthy brain aging. Use it or lose it! Pilot study by Alzheimers Australia (WA) finds regular brain exercises are the key to healthy ageing Just two hours of brain exercises a week can markedly improve a person’s...

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Higher leptin levels, lower Alzheimer's incidence Persons with higher levels of leptin, a protein hormone produced by fat cells and involved in the regulation of appetite, may have an associated reduced incidence of Alzheimer disease and dementia, according...

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How our brain learns

Posted by Jim Hanekamp | Posted in Brain, Hippocampus, Memory, Neurogenesis | Posted on 20-11-2009

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The ability of humans to learn, remember, and adapt is directly related to the changeableness (plasticity) of the human brain. Whenever we learn new information, the connections between nerve cells in the brain are modified. The activity of some connections (called synapses) increases, while the activity of other synapses decreases. The initial changes involve local chemical alterations in the way synapses transmit and receive information from other neurons. These initial chemical changes eventually lead to structural changes in the brain; that is, more connections and more complex connections form. The longer lasting of these changes require the turning on and turning off of specific genes; therefore, learning involves gene expression. Changes in synaptic connections represent a major way by which memories are formed. But some memories fade, and it is likely that the newly formed connections must be reinforced by ongoing brain activity in order for these connections to survive. The important points to remember are that learning alters the actual structure of the brain and that genes are involved in learning.

Neurogenesis

Neurogenesis (the formation of new nerve cells in the adult brain) is really part of the larger story about brain plasticity. Neurogenesis reflects the amazing resilience and plasticity of our brains. Expanding upon observations initially made years ago about birds, it has become clear that certain parts of the human brain are capable of generating new neurons throughout life, even during old age.  Not all regions of the brain appear to have this ability to grow new nerve cells, but two regions, the dentate gyrus of the hippocampus and the areas near the lateral ventricles in the olfactory system (which is involved in the sense of smell), are really good at it. The dentate gyrus plays a key role in the function of the hippocampus, the region that is so critical for memory processing. A thousand or more new neurons are born in this region each day and can be incorporated into the circuitry of the hippocampus where they help enhance certain types of learning. These new neurons may be particularly important for processing new information.

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Simple technique to boost creativity

Posted by Jim Hanekamp | Posted in Brain, Mental exercise | Posted on 16-11-2009

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There have been prior clues that creativity benefits from ample cross-talk between the brain hemispheres. For example, patients who’ve had a commissurotomy – the severing of the thick bundle of nerve fibers that joins the two hemispheres – show deficits on creative tasks. Now Elizabeth Shobe and colleagues have provided the first evidence that creativity is boosted by an intervention designed to increase hemispheric cross-talk.

Shobe’s team tested 62 participants on a version of the “Alternative Uses Test”, a divergent thinking challenge that involves dreaming up unconventional uses for everyday objects such as bricks and newspapers.

An important factor that the researchers took note of was the participants’ handedness. Prior research has suggested that people who have one hand that is particularly dominant, so-called “strong-handers”, have less cross-talk between their brain hemispheres compared with people who are more ambidextrous or “mixed handed”.

After an initial attempt at the creativity task, half the participants spent thirty seconds shifting their eyes horizontally back and forth. This exercise is thought to help increase inter-hemispheric communication. The remaining participants acted as controls and just stared straight ahead for 30 seconds.

The key finding is that on their second creativity attempt, strong-handers who’d performed the horizontal eye movements subsequently showed a significant improvement in their creativity, in terms of being more original (i.e. suggesting ideas not proposed by others) and coming up with more categories of use. Staring straight ahead, by contrast, had no effect on creativity.

Another finding was that, overall, the mixed-handed participants performed better on the creativity task than the strong-handers, thus providing further evidence for a link between inter-hemispheric interaction, which mixed-handers have more of, and creativity. But it also turned out that mixed-handers didn’t benefit from the horizontal eye movement task. It’s as if they already have an optimum amount of hemispheric cross-talk so that the eye movements make no difference. This meant that after the strong-handers had performed the horizontal eye movements, their performance matched that of the mixed-handed participants.

The researchers also showed that, for strong-handers, the beneficial effects of the eye movement exercise lasted nine minutes for originality, but just three to six minutes in terms of coming up with more categories of use.

“Our findings may not apply to more unique populations who are characterized as ‘highly creative’,” the researchers said, “nor can we conclude … that the thirty seconds bilateral eye movement task will turn an average individual into an artist, poet, scientist, philosopher, actor or sculptor. However, we certainly do propose that the … eye movement task will result in a temporary increase in strong-hander’s ability to think of creative uses for various house-hold objects.”

These new findings complement research published in 2008 showing that horizontal eye movements aid memory performance for strongly-right handed people, but impair the performance of left-handers and mixed-handers.

See original article here

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Drink tea and improve brain power

Posted by Jim Hanekamp | Posted in Aging, Brain, Dementia, Hippocampus, Memory, Nutrition | Posted on 10-11-2009

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Drinking eight cups of tea daily might sound a bit too much for some people, but health experts say the intake can help fight heart disease, improve brain power and also boost longevity.

Independent Dietician, Dr. Carrie Ruxton’s research on caffeine at King’s College, London, saw her review 47 published studies to reach the conclusion that caffeinated drinks such as tea, coffee and cocoa have positive effects on mental function, increasing alertness, feelings of well-being and short-term memory.

Previous studies have already linked the drink’s healthy antioxidant properties and high flavonoid content to preventing heart disease and cutting the risk of some cancers.

Ruxton has supported earlier reports by claiming that an optimal intake of 400mg of caffeine a day leads to “key benefits in terms of mental function and heart health”.

She assessed three studies, accounting for almost 90,000 patients, to find that drinking four cups of tea or coffee a day reduced chances of cardiovascular disease.

She referred to another study of 26,500 middle-aged smokers, which hinted that men who ingested more than two cups of tea a day pulled down the probability of getting a stroke by 20 percent.

Ruxton insisted that she aimed to “debunk” false beliefs surrounding caffeine.

Moreover, she asserted that people who avoid drinking team might be doing more harm than good.

“People who cut out caffeinated drinks may miss out on the potential health benefits of the compounds they contain,” the Daily Express quoted her as saying.

She further suggested that there was “no need” for parents to stop children from drinking tea and coffee. In fact, she claimed it was better than juice in some regards.

Also, Dr Catherine Hood, of the Tea Advisory Panel, agreed to Ruxton’s claims.

She said, “Caffeinated drinks have been unfairly demonized. Black tea, in particular, contains polyphenols, which are natural plant antioxidants.”

“These have beneficial effects on many biochemical processes in the body because they protect cells against harmful free radicals.” she said.

“Flavonoids are thought to be especially useful, with a number of studies reporting a link between them and lower risk of heart attack.” she added.

Another way to improve your brain is push your brain in novel ways by playing Myfitbrain.

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Help your new brain cells to survive

Posted by Jim Hanekamp | Posted in Brain, Brain games, Cognitive games, Dementia, Hippocampus, Memory, Neurogenesis | Posted on 09-11-2009

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By Catherine E. Myers, Ph.D.

Every day, new brain cells (neurons) are born in the brains of adult mammals, a process called neurogenesis (neuro = neurons, genesis = birth).  These newborn cells appear particularly in the hippocampus – a brain area that is important for new memory formation.   Over the next few weeks, many of these newborn cells die off again.  But studies show that, if a rat has been exercising or has been exposed to new learning, more of the newborn cells survive.  The rate of survival of these new cells also depends on sleep.

As we sleep, we (like rats) cycle through several “stages,” including rapid-eye movement (REM) sleep, which is believed to be when we dream, and several kinds of non-REM sleep.

A recent study has suggested that REM is particularly important for neurogenesis in the hippocampus.  One group of rats were given four days of REM deprivation, by putting the rats in a small chamber where the floor was a treadmill that automatically activated whenever the rats entered REM sleep – forcing them to step forward to avoid being carried into the wall of the chamber.  (Non-REM sleep didn’t activate the treadmill.) For comparison, a group of control rats were placed in the same type of chamber, but treadmill activation was unrelated to sleep cycle.

The REM-deprived rats showed much less neurogenesis than controls. Both groups showed similar amounts of total sleep, and similar levels of stress hormones, indicating that the stress of being periodically awoken was similar for the REM-deprived and control rats. This study therefore suggests that REM sleep is particularly important for the birth and survival of new neurons in the adult brain.

There are two important implications of this study.  The first is that it adds to a growing literature suggesting that relatively short-term periods of sleep deprivation (equivalent to a few nights’ insomnia or intentional wakefulness) can significantly affect the brain.  This is a cautionary finding for those of us who routinely don’t get a full night’s sleep.

The second implication is that not all sleep is equal.  This study also adds to a growing literature suggesting that REM sleep has some special functions, particularly contributing to learning and memory.  Many medications, including some over-the-counter sleeping aids, disrupt REM sleep.  If REM sleep is indeed important for neurogenesis, then disrupting REM may disrupt neurogenesis – which might in turn have consequences for a person’s learning and memory abilities.

Further Reading:

R. Guzman-Marin et al. (2008). Rapid eye movement sleep deprivation contributes to reduction of neurogenesis in the hippocampal dentate gyrus of the adult rat. Sleep, 31(2):167-175.

Help your brain cells to survive with novel learnings from Myfitbrain

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Reduce anxiety by playing brain games

Posted by Jim Hanekamp | Posted in Anxiety, Brain, Brain games, Depression, Mental exercise | Posted on 04-11-2009

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Mindless distractions might not reduce anxiety as effectively as a brain teaser.

A brain-imaging study published last year by Nature Neuroscience suggests such brain-sharpening activities as crossword puzzles reduce anxiety by activating a region of the brain devoted to logic and concentration — the prefrontal cortex.

“This is being supported by burgeoning neuropsychologic data,” said Dr. Carl Aagesen, a psychiatrist at Medical Associates Clinic. “The prefrontal cortex is used for planning, making judgments and delaying impulses. This part of our brain is how we do self-talk to turn down input from the amygdala.”

The amygdala is the source of the brain’s “fight-or-flight reflex,” which alerts the body to protect itself in times of danger and is thought to contribute to feelings of anxiety.

Surveys indicate one in five adults experience above-average levels of anxiety annually and research has shown anxious people struggle to concentrate.

Sonia Bishop, a UC Berkeley psychologist and lead author of the brain imaging study, used functioning Magnetic Resonance Imaging to study 17 men and women, ranging in age from 19 to 48, at Cambridge University. They scored in standardized tests as having varying levels of anxiety, but were not on medication.

Their brains were scanned as they performed letter-searching tasks. When the letter search was demanding, brain scans showed all the study participants’ dorsolateral prefrontal cortexes, which control planning, organization and memory, to be fully engaged.

But when the letter search was easy, the prefrontal brain activity in high-anxiety participants plummeted as their attention wandered.

In contrast, low-anxiety participants easily activated the prefrontal brain to focus on the task at hand when presented with distractions. Aagesen describes the brain as functioning like a computer. “It cannot do two things simultaneously, but it can shift back and forth almost instantaneously,” he said.

Crossword puzzles, math games, mazes and other brain-teasing activities actively engage the prefrontal cortex — which can calm anxiety.

“The more you engage the dorsolateral prefrontal cortex actively, the more you are able to shut down input from the fear centers, because you can’t do two things at once,” Aagesen said.

If you want to reduce your anxiety, try Myfitbrain brain games.

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Brain protection done naturally

Posted by Jim Hanekamp | Posted in Brain, Hippocampus, Mental exercise, Neurogenesis, Parkinson's Disease, Physical exercise | Posted on 30-10-2009

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By Laura Sanders, Science News

CHICAGO — A toned, buff bod isn’t the only thing a workout is good for. Exercise protects special brain cells in monkeys’ brains and improves motor function, a new study finds. The data, presented at a news briefing October 18 in Chicago at the Society for Neuroscience’s annual meeting, adds to a growing body of evidence that shows exercise is good for the brain, too.

“This is sort of a quiet revolution that’s been occurring in neuroscience,” says Carl Cotman, a brain aging expert at the University of California, Irvine, “to realize that physical activity at a certain level impacts the brain in a really profound way.”

In the new study, researchers led by Judy Cameron of the University of Pittsburgh trained six adult female rhesus monkeys to run on treadmills built for humans. Over a period of three months, monkeys either ran, jogged or sat on a treadmill for five hours each week. Monkeys that ran got their heart rates to about 80 percent of maximum, comparable to a human training program that would increase cardiovascular fitness. The jogging monkeys’ heart rates reached about 60 percent of maximum.

After this training period, the researchers hit the right side of the monkeys’ brains with a neurotoxin called MPTP, designed to selectively kill neurons that produce the signaling chemical dopamine. These neurons, and the dopamine they produce, regulate movement, and are the very same ones that die in people with Parkinson’s disease.

Sedentary monkeys showed the expected decrease in these dopamine neurons on the right side of the brain after the neurotoxin was applied. But in the brains of monkeys that had run for the past three months, the neurotoxin had almost no effect. In the runners, dopamine neurons were just as plentiful on the right side of the brain as on the left.

Jogging also had a protective effect, although slightly weaker than running’s, Cameron says. “This is really good news. It means that any little bit more activity you can do is positive for your brain,” says Cameron. “Your brain seems very sensitive to exercise.”

When the researchers continued the experiment for another six weeks, the results held. A brain scan revealed that “the animals that were exercising had virtually no loss of dopamine in those neurons,” Cameron says. “We think that exercise is very neuroprotective.”

Next, the researchers assessed the monkeys’ ability to use the hand affected by the neurotoxin. Monkeys had to retrieve a Lifesaver candy from a thin wire, an experiment designed to test motor coordination. Sedentary monkeys could not use their left, affected hand at all, while the runners showed no difference between their left and right hands, the researchers found.

The new study highlights the importance of exercise for maintaining a healthy brain. Other studies presented at the meeting have found that exercise has a wide range of brain-protective roles in mice, monkeys and humans.

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Your brain excels when you give it good nourishment, physical exercise, keep the stress down, get the right amount of sleep, and push it novel directions like using Myfitbrain.

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Improve your willpower

Posted by Jim Hanekamp | Posted in Brain, Meditation | Posted on 28-10-2009

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By Daniel Goleman & Greater Good Magazine

Those of us who struggle to resist junk foods or otherwise suffer a lack of willpower will be heartened by some good news from neuroscience. But there’s some bad news, too.

First, the bad news. A slew of studies suggest that we each have a fixed neural reservoir of willpower, and that if we use it on one thing, we have less for others. Tasks that demand some self-control make it harder for us to do the next thing that takes willpower.

In a typical experiment on this effect, one group of people was made to watch a video of a boring scene; another was not. Then both groups had to circle every “e” in a long passage of writing. The result? The people who had to first sit through the boring video gave up faster. The same loss of persistence has been found when people try to resist tempting foods, suppress emotional reactions, or even make the effort to try to impress someone.

This all suggests we have a fixed willpower budget, one we should be careful in spending. Some neuroscientists suspect that self-control consumes blood sugar, which takes a while to build up again; thus, the depletion effect.

But the good news is that we can grow our willpower; like a muscle, the more we use it, the more it gradually increases over time. But doing this takes, of all things, willpower.

As the muscle of will grows, the larger our reservoir of self-discipline becomes. So people who are able to stick to a diet or an exercise program for a few months, or who complete money-management classes, also reduce their impulse-buying, junk food consumption, and alcohol intake. They watch less TV and do more housework. And this ability to delay grasping at gratification, much data shows, predicts greater career success.

This round-up of thinking on willpower comes courtesy of Sandra Aamodt and Sam Wang, whose recent book, Welcome to Your Brain, details the evidence about willpower. But, writing in The New York Times, the duo poses a puzzle: While it’s clear that willpower has limits, what brain mechanisms let us build it up?

That question brought to mind a recent conversation I had with Richard Davidson, the director of the Laboratory for Affective Neuroscience at the University of Wisconsin. Davidson’s research these days focuses on neuroplasticity—how our experience shapes the brain throughout life. One surprise: though most of us learned that we have a fixed number of brain cells when we are born, and that we lose them steadily until we die, brain science now tells us the brain makes about 10,000 new cells every day, and that they migrate to where they are needed. Once there, each cell makes around 10,000 connections to other brain cells over the successive four months.

Davidson’s research finds that the left prefrontal cortex—the brain’s executive center located just behind the forehead—is a key site for helping us build willpower. Our plans and goals hatch here, and impulses are executed via this zone. There is a neural circuit in the prefrontal cortex that inhibits emotional impulse, and can be strengthened by a range of methods.

One of these methods, Davidson explained to me, is mindfulness training, a secular form of meditation widely used in settings from businesses to outpatient clinics. This is confirmed by a great deal of research. My own doctoral dissertation found (as have many others since) that the practice of meditation seems to speed the rate of physiological recovery from a stressful event. A string of studies have now established that more experienced meditators recover more quickly from stress-induced physiological arousal than do novices.

Research shows that other kinds of training can have similar effects, and the more time we devote to any of these trainings, the greater the result in the targeted areas of the brain. Brain imaging studies show that the spatial areas of London taxi drivers’ brains become enhanced during the first six months they spend driving around that city’s winding streets; likewise, the area for thumb movement in the motor cortex becomes more robust in violinists as they continue to practice over many months. A seminal 2004 article in the Proceedings of the National Academy of Science found that, compared to novices, highly adept meditators generated far more high-amplitude gamma wave activity—which reflects finely focused attention—in areas of the prefrontal cortex while meditating.

And so it makes perfect sense that we can build our willpower over time if we are committed to doing so, a process that changes our brains right down to the cellular level. Simply being consistently self-disciplined seems to help—going to the gym every day for months, or completing projects you begin—and so does mindfulness mediation. There are ways, it seems, to make it easier to “just say no” when we need to.

See the original article here.

We need to use our willpower to keep our body fit through exercising and eating right and our mind fit by meditating and exercising it using tools like Myfitbrain.

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